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观察苯磺酸左旋氨氯地平与依那普利联合治疗原发性高血压的疗效
作者:陈芳 李皓
来源:《中国实用医药》2015年第11期
【摘要】 目的 观察苯磺酸左旋氨氯地平联合依那普利治疗原发性高血压的临床疗效。方法 105例原发性高血压患者随机分为A、B、C三组, 各35例, 分别给予单用苯磺酸左旋氨氯地平、依那普利以及两者联合。连续治疗4周后, 进行疗效对比。结果 C组降压总有效率97.14%, 明显高于A组82.86%和B组68.57%, 差异有统计学意义(P 【关键词】 苯磺酸左旋氨氯地平;依那普利;原发性高血压;疗效分析 DOI:10.14163/j.cnki.11-5547/r.2015.11.007
Observation of curative effect by levamlodipine besylate and enalapril in combined treatment of primary hypertension CHEN Fang, LI Hao. Guangzhou City Huangpu District Huangpu Street Community Health Service Center, Guangzhou 517000, China
【Abstract】 Objective To observe the clinical effect of levamlodipine besylate combined with enalapril in the treatment of primary hypertension. Methods A total of 105 primary hypertension patients were randomly divided into group A, group B and group C, with 35 cases in each group. Treatment was given to the three groups as single levamlodipine besylate, enalapril, and their combination. After 4 weeks treatment, their curative effects were compared. Results The total anti-hypertension effective rate of group C was 97.14%, which was obviously higher than 82.86% of group A and 68.57% of group B. The difference had statistical significance (P
【Key words】 Levamlodipine besylate; Enalapril; Primary hypertension; Curative effect analysis
原发性高血压病是我国心血管慢性疾病中最为常见的一种, 如控制不好可直接影响心、脑及肾等人体的重要脏器功能, 长期将导致患者心肌梗死、心力衰竭和慢性肾脏疾病等。目前, 临床上常用苯磺酸左旋氨氯地平和依那普利降压, 两者通过不同的途径达到其降压效果[1]。本次研究通过对本院收治的105例原发性高血压患者采用苯磺酸左旋氨氯地平与依那普利分别单用和联合进行治疗, 现将结果报告如下。 1 资料与方法
1. 1 一般资料 选择2012年10月~2014年1月在本院治疗的原发性高血压患者105例, 且均符合该疾病的相关诊断标准[2], 同时排除继发性高血压、糖尿病、严重肝肾功能障碍及
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