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肺结核合并呼吸衰竭行小潮气量机械通气的疗效分析
作者:吴恩东 宋丽红 韩芬 张楠 刘秋月 王秀军 来源:《中国医药导报》2015年第29期
[摘要] 目的 探讨小潮气量机械通气与常规潮气量机械通气治疗肺结核合并呼吸衰竭的临床效果。 方法 选取2011年1月~2014年4月首都医科大学附属北京胸科医院收治的肺结核合并呼吸衰竭患者96例,按照随机数字表法分为观察组和对照组,各48例。在常规治疗的基础上,观察组患者给予小潮气量机械通气治疗,对照组患者给予常规潮气量机械通气治疗,比较两组相关血气分析指标、机械通气时间、气压伤发生情况及预后情况。 结果 通气前,两组相关血气分析指标比较,差异无统计学意义(P > 0.05);通气后24 h,两组pH、氧分压(PaO2)明显比通气前高,二氧化碳分压(PaCO2)明显比通气前低,差异有高度统计学意义(P < 0.01);通气后24 h,两组pH比较,差异无统计学意义(P > 0.05);通气后24 h,观察组PaCO2、PaO2明显比对照组高,差异有高度统计学意义(P < 0.01)。观察组机械通气时间短于对照组,差异有高度统计学意义(P < 0.01)。观察组气压伤发生率低于对照组,差异有统计学意义(P < 0.05)。两组预后情况比较,差异有统计学意义(P < 0.05)。 结论 小潮气量机械通气治疗肺结核合并呼吸衰竭可有效提高患者的动脉血PaO2,降低气压伤发生率和死亡率,值得临床应用。
[关键词] 小潮气量;机械通气;肺结核;呼吸衰竭;呼吸机相关性肺损伤 [中图分类号] R521 [文献标识码] A [文章编号] 1673-7210(2015)10(b)-0097-04 Curative effect analysis of low tidal volume mechanical ventilation in pulmonary tuberculosis complicated with respiratory failure
WU Endong1 SONG Lihong2 HAN Fen1 ZHANG Nan1 LIU Qiuyue1 WANG Xiujun1▲ 1.Intensive Care Unit, Beijing Chest Hospital Affiliated to Capital Medical University, Beijing 101149, China; 2.Department of Internal Medicine Ward 2, Beijing Chest Hospital Affiliated to Capital Medical University, Beijing 101149, China
[Abstract] Objective To investigate clinical effect of low tidal volume mechanical ventilation and conventional tidal volume mechanical ventilation in the treatment of pulmonary tuberculosis complicated with respiratory failure. Methods 96 cases of patients with pulmonary tuberculosis
complicated with respiratory failure in Beijing Chest Hospital Affiliated to Capital Medical University from January 2011 to April 2014 were selected. And the patients were divided into observation group and control group according to the random number table method, each group of 48 cases. On the basis of conventional therapy, observation group was treated with low tidal volume mechanical
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