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大肠埃希菌肠道外感染及其治疗的研究近况
作者:杨君洋 卢洪洲
来源:《上海医药》2016年第07期
摘 要 大肠埃希菌是人类常见的肠道致病菌,其感染主要引起腹泻。但在一定条件下大肠埃希菌也可造成尿路、腹腔、胆道,肺部和血流感染等肠道外感染,且其临床表现因感染部位的不同而不同。抗菌治疗是大肠埃希菌肠道外感染的主要治疗措施,必要时还可予以手术治疗。本文主要就大肠埃希菌肠道外感染的临床表现及治疗予以综述。 关键词 大肠埃希菌 临床表现 治疗
中图分类号:R516 文献标识码:A 文章编号:1006-1533(2016)07-0021-04
Research progress of the extraintestinal infection caused by Escherichia coli and its treatment* YANG Junyang1,2, LU Hongzhou1,3,4**
(1. Department of Infection Diseases, Shanghai Public Health Clinical Center, Shanghai 201508, China; 2. Department of Graduate School, Wenzhou Medical University, Zhejiang 325000, China; 3. Department of Infection Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China; 4. Department of Internal Medicine, School of Medicine, Fudan University, Shanghai 200032, China)
ABSTRACT Escherichia coli (E. coli) is an common enteric pathogen and can cause intestinal disease, usually diarrhea. However, E. coli can also cause extraintestinal infections, such as urinary, abdominal, biliary, pulmonary and, bloodstream infections and so on under the certain conditions, of which clinical symptoms vary because of the differences of the infectious site. Antibiotic therapy is a main way for the treatment of E. coli extraintestinal infection. Surgery can also be used for the treatment of E. coli extraintestinal infection when necessary. The advances in E. coli infection and its treatment are reviewed in this article.
KEY WORDS Escherichia coli; clinical symptoms; treatment
大肠埃希菌(Escherichia coli,E. coli)是正常人结肠内主要的寄生菌,也是人类常见的肠道致病菌。但在少数情况下,E. coli还可引起肠道外感染,如E. coli可通过污染尿道上行感染泌尿系统引起膀胱炎甚至肾盂肾炎,或经血液系统和淋巴系统下行感染引起肾脏感染;E. coli也可自血液达到胆囊,或经门静脉感染;E. coli还可透过肠壁感染腹腔引起腹膜炎。 1 E. coli肠道外感染的临床表现
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