曲美他嗪联合地尔硫卓治疗心绞痛的疗效

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曲美他嗪联合地尔硫卓治疗心绞痛的疗效

作者：郭锦祥

来源：《中国医药科学》2012年第22期

[摘要] 目的 观察曲美他嗪联合地尔硫卓治疗心绞痛的疗效。 方法 选取笔者所在医院心绞痛患者50例，随机分为治疗组和对照组。对照组给予休息、吸氧、镇静、抗凝和抗血小板聚集等常规抗心绞痛处理，治疗组在此基础上，给予口服曲美他嗪片和地尔硫卓片，治疗2周后观察疗效和心电图情况。 结果 治疗组总有效率88%，对照组总有效率64%，治疗组疗效明显高于对照组，差异有统计学意义（P [关键词] 曲美他嗪；地尔硫卓；心绞痛

[中图分类号] R541 [文献标识码] B [文章编号] 2095-0616（2012）22-70-02 Curative effect of trimetazidine combined with diltiazem for angina GUO Jinxiang

Department of Internal Medicine， Datong Coal Mine Group Silaogou Mine Hospital， Datong 037028， China

[Abstract] Objective To observe the curative effect of trimetazidine combined with diltiazem for angina. Methods 50 patients with angina were randomly divided into treatment group and control group. The control group was given conventional antianginal treatment， ex rest， oxygen uptake， sedation， anticoagulant and antiplatelet aggregation. The treatment group was given oral

trimetazidine and diltiazem tablets on the basis of the control group. The curative effect and ECG information of two groups were observed after 2 weeks. Results The total effective rate of treatment group was 88%， and the total effective rate of control group was 64%. The curative effect of treatment group was obviously higher than that of control group （P [Key words] Trimetazidine； Diltiazem； Angina

心绞痛是冠状动脉粥样硬化引起的血管腔狭窄、阻塞、痉挛，导致心肌发生缺血缺氧，严重威胁人类的生命健康。在临床上，可分为稳定型心绞痛和不稳定型心绞痛，一般通过改善心肌血流，增加氧的供给，减少心梗的发生率，是主要的治疗方法。笔者使用曲美他嗪联合地尔硫卓对心绞痛患者进行治疗，效果满意，现报道如下。 1 资料与方法 1.1 一般资料